This Article explores the adaptation of user interfaces (UIs) to enhance accessibility and inclusion, examining the design principles, methodologies, and tools essential for creating inclusive digital experiences. By analyzing both quantitative data and qualitative insights, the study identifies effective strategies for making UIs accessible to diverse user groups, including those with disabilities. The findings highlight the significance of accessibility in UI design, demonstrating how inclusive practices improve user satisfaction and broaden market reach. The study's implications stress the need for ongoing attention to accessibility in the digital design process to foster a more inclusive digital environment.